Calcified Epithelioma

Calcified Epithelioma
Body Parts: Head Neck Upper Limbs
Medical Subjects: Skin

What Is Calcified Epithelioma

What is calcified epithelioma?

Calcified epithelioma is a benign tumor that occurs on the skin.

Calcified epithelioma is called because it originates from epithelial hyperplasia and calcification is often found inside the tumor. It is also called piloblastoma because the hyperplastic epithelial cells differentiate into piloblastoma.

Is calcified epithelial tumor common?

At present, the incidence rate of calcified epithelioma has not been clarified. According to a study report, the incidence rate of calcified epithelioma found in pathological examination results of all skin biopsy tissues ranged from 1/100,000 to 3.1/100,000.

Therefore, calcified epithelioma can be described as a rare skin tumor.

Is calcified epithelioma benign or malignant?

Calcified epithelioma is a benign tumor that, in very rare cases, may malignant change to a pilocytic carcinoma.

Then under what circumstances should we be vigilant against malignant transformation of calcified epithelioma?

First, the tumor volume increases rapidly (greater than 4 cm in diameter);

Second, imaging (ultrasound, CT or MRI) reveals a deep tumor invasion (up to the fascial layer of the skin or skeletal muscle), which needs to be judged by a professional doctor.

Does calcified epithelial tumor meet heredity?

Calcified epithelioma is not hereditary. However, multiple calcified epithelioma may be associated with some genetic syndromes, such as congenital ovarian agenesis syndrome and Gardner syndrome.


What Is The Etiology Of Calcified Epithelioma

Why can get calcified epithelial tumor?

At present, it is generally believed that calcified epithelioma is caused by the mutation of CTNNB1 gene encoding β -catenin.

β -catenin plays a role in cell proliferation, so mutations in this gene can cause hyperproliferation of cells, leading to the development of calcified epithelioma.

Who is easy to get calcified epithelial tumor?

Calcified epithelioma can occur in any age group but presents two peaks, the first in children and adolescents and the second in adults over the age of 50 years.

The incidence in women is slightly higher than in men.

In addition, some patients with genetic syndrome are prone to multiple calcified epithelioma.


What Symptom Does Calcified Epithelial Tumor Have

What are the common symptoms of calcified epithelioma?

Calcified epithelioma usually presents as a single, hard, hemispherical nodule with a skin to bluish-gray surface, most preferably occurring in the head and neck (64%), followed by the upper limb (22%).

Most patients do not experience discomfort, and some patients (16.7%) may experience tenderness, while a few patients (3.0%) may rupture the mass and expel the contents to the surface.

Calcified epithelioma grows slowly and is usually 0.5–3cm in diameter. As mentioned, if the mass increases rapidly or exceeds 4cm in diameter, you should be alert to malignant changes.

What serious consequences can calcified epithelioma cause?

The most serious consequence of calcified epithelioma is malignant transformation. Fortunately, however, the malignant transformation of calcified epithelioma results in low-grade malignant piloblastic carcinoma with low risk of metastasis.

As calcified epithelioma occurs frequently in the face and neck, its excessive growth may cause facial damage and affect the social interaction of patients.


How To Check For Calcified Epithelioma

How is calcified epithelial tumor diagnosed?

The diagnosis of calcified epithelioma requires skin biopsy.

This is an invasive procedure that requires local injection of an anesthetic followed by removal of a mung bean-sized piece of skin and microscopic observation of the lesion to confirm a calcified epithelioma.


How To Prevent Calcified Epithelioma

How does calcified epithelioma prevent or relapse?

At present, there is no way to prevent the occurrence of calcified epithelioma, but its recurrence can be prevented by complete resection.


How To Treat Calcified Epithelioma

What branch should calcified epithelial tumor see?

The diagnosis of various skin masses should be confirmed by dermatological consultation, including calcified epithelioma.

Once the diagnosis is made and the need for excision is identified, dermatology or plastic or general surgery with the ability to remove the skin mass can be selected.

What treatment method does calcified epithelial tumor have?

Calcified epithelioma does not resolve itself and can only be removed by surgery.

Resection requires an appropriate resection edge to ensure complete resection, and tumor remnants may cause recurrence or even malignant transformation.

Will calcified epithelial tumor recur after surgical excision?

Surgical resection can generally cure calcified epithelioma with appropriate resection margin, but local recurrence may still occur in 2%–3% of patients.


What Should Calcified Epithelial Tumor Patient Notice In Life

What does calcified epithelial tumor patient need to notice everyday?

Calcified epithelioma is a local mass of the skin, and care should be taken to avoid scratching in life, otherwise it will be easy to become inflamed and infected, and attention should be paid to the growth rate of the tumor.

If the resected patient is not considered, a photograph can be taken annually to record the size of the tumor, and if there is no significant change, the tumor can be left untreated and continued to be observed.

In the diet, calcified epithelioma has no special need to pay attention to, it is enough to maintain a healthy diet, such as hun vegetable collocation, avoid high salt and high sugar and spicy food, drink less, etc.

If a calcified epithelioma is excised, what needs to be noticed during excision?

If we decide to remove the calcified epithelioma, we must first ensure that the skin lesion is in a non-infectious state, that is, there is no swelling, tenderness, and so on. If we cannot judge by ourselves, it is up to the doctor to judge.

Second, regular hospital is selected for resection. The calcified epithelioma needs complete resection to reduce the probability of recurrence.

Excision of a calcified epithelioma is a local anesthesia procedure in which food and water are normally consumed preoperatively. After the resection of local need to avoid touch water, the next day the dressing, stitches after 1 ~ 2 weeks (according to the resection site to determine the specific time of stitches).

If you are especially worried about leaving scars, you can use external medicines for removing scars after removing the stitches, such as beautiful skin care, Kehen, Kangruibao and so on (one can be selected), and you can insist on using for more than half a year.

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