Exfoliative Dermatitis

Exfoliative Dermatitis
Medical Subjects: Skin

What Is Exfoliative Dermatitis

What is exfoliative dermatitis?

Exfoliative dermatitis is a skin disease that can cause more than 90% of the skin of the whole body to produce inflammatory manifestations, such as flushing, swelling and desquamation of the skin, accompanied by fever and other symptoms. It is also called "erythroderma" because of its typical manifestation of flushing of the whole body skin.

Exfoliative dermatitis is not an independent disease in fact, it is a clinical manifestation of many diseases, and many diseases can lead to exfoliative dermatitis.


What Is The Cause Of Exfoliative Dermatitis

What are the causes of exfoliative dermatitis?

There are many causes of exfoliative dermatitis, and the common ones are as follows:

  • Improper treatment of skin diseases and long-term development can lead to exfoliative dermatitis, such as psoriasis, eczema, atopic dermatitis, etc.。

  • Medications can also cause exfoliative dermatitis (see next question).

  • Some tumors can cause exfoliative dermatitis, such as malignant lymphoma Hodgkin's disease, skin T-cell lymphoma, leukemia, etc.

  • Some hereditary diseases, such as ichthyosis, can also lead to exfoliative dermatitis.

  • Another part of exfoliative dermatitis for which the cause cannot be found at present is idiopathic exfoliative dermatitis (the disease for which the cause cannot be found is named as idiopathic disease in medicine).

Which medicaments is exfoliative dermatitis easy to cause?

There are a variety of drugs that cause exfoliative dermatitis, to name a few common ones:

  • Antibiotics, such as penicillin, amoxicillin, sulfonamides.

  • Psychotropic substances such as phenytoin and phenobarbital.

  • A drug, such as allopurinol, used to treat gout.

  • Chinese medicinal materials, such as qingkailing injection, folium ginkgo, realgar, and Scorpio.

  • Some heavy metals, such as mercury, gold, and bismuth (some Chinese medicinal materials contain heavy metals).

With the increasing varieties of drugs, exfoliative dermatitis caused by drug allergy is also increasing.

What are the causes of exfoliative dermatitis in infants and young children?

In infants and young children, ichthyosis, immunodeficiency, psoriasis and infection (staphylococcal scalded skin syndrome) are the leading causes of exfoliative dermatitis, which is sometimes attributed to drugs.

Exfoliative dermatitis easy to happen in which population?

Studies have shown that men appear to be more susceptible to exfoliative dermatitis than women, with a ratio of approximately 2:1 to 4:1.


What Symptom Does Exfoliative Dermatitis Have

What are the most important symptoms and manifestations of exfoliative dermatitis?

Exfoliative dermatitis is acute and chronic, with different manifestations:

  • Acute exfoliative dermatitis: The disease is acute. First, there appeared a wide and dense rash on the skin, which rapidly increased and then merged into sheets and became flushing with edema all over the body, with fine bran-like or flaky desquamation. The face and four limbs were the most obvious. Sometimes, the skin like gloves could be peeled off from the palm or sole. In severe cases, cracks appear in the limbs and joints, and erosion occurs in the mouth, groin and axilla, often accompanied by severe itching.

  • Chronic exfoliative dermatitis: The disease lasts for a long time, and the skin shows large flushing and swelling with desquamation.

Does exfoliative dermatitis have other expression besides the expression that has skin?

In addition to cutaneous manifestations, patients with exfoliative dermatitis may present with the following:

  • Congestion, erosion and ulcer of oral mucosa;

  • Keratitis or corneal ulcer;

  • Alopecia, nail thickening;

  • Lymph node enlargement, hepatosplenomegaly;

  • Kidney damage: hematuria, proteinuria and even renal failure;

  • Cardiovascular problems: Heart rate failure and lower limb edema may occur;

  • Endocrine problems: Male testicular atrophy and feminization of breast may appear, while female may have menstrual disorders and hyperplasia of mammary glands.

Why is patient of exfoliative dermatitis afraid of cold?

Patients with exfoliative dermatitis, because the skin blood flow increases, heat dissipation is more, a large amount of heat loss in the body, so easy to appear afraid of cold cold symptoms, sometimes with chills. In addition, exfoliative dermatitis combined with infection can lead to fever, but also with chills and chills.

Why is exfoliative dermatitis patient easy companion hair infection?

  • First, the skin barrier of patients with exfoliative dermatitis is damaged, and thus the skin is susceptible to infection.

  • In addition, because repeated desquamation for a long time leads to the loss of a large number of proteins, resulting in hypoproteinemia and decreased resistance of patients, systemic infection is easy to occur.

Is exfoliative dermatitis serious?

Exfoliative dermatitis is a serious disease that can lead to death.

  • Exfoliative dermatitis caused by general drugs, stop using drugs that cause allergies, symptomatic treatment, the prognosis is very good, generally will heal, severe skin pigmentation may be left, generally in 1 ~ 2 months will fade.

  • Chronic exfoliative dermatitis caused by psoriasis, eczema and others has a poor prognosis, which can last for several months to several years, and is prone to relapse. The patients' immunity is decreased, and they are prone to infection and have more complications.

  • Exfoliative dermatitis caused by malignant tumors may die because the tumors are not treated effectively.

Does exfoliative dermatitis have sequela?

After exfoliative dermatitis is cured, sequela are very few.

  • After the acute exfoliative dermatitis improves, the pigmentation may be left, and it takes 1–2 months for the pigmentation to gradually disappear.

  • Chronic exfoliative dermatitis may result in thinner skin, increased heat loss, and patients being more afraid of the cold and more susceptible to infection than normal people.


How To Check For Exfoliative Dermatitis

How is exfoliative dermatitis diagnosed?

Exfoliative dermatitis is easy to diagnose and can be diagnosed with the appearance of large areas of skin flushing, edema, and associated desquamation or peeling. However, the diagnosis of exfoliative dermatitis is not complete. The most important thing is to find the cause of exfoliative dermatitis before targeted treatment can be carried out.


How To Prevent Exfoliative Dermatitis

How to prevent exfoliative dermatitis?

  • Not all exfoliative dermatitis can be prevented, and some exfoliative dermatitis secondary to other diseases or drugs can be theoretically prevented.

  • Psoriasis, eczema patients, should pay attention to the use of drugs under the guidance of the doctor, do not abuse the drug.

  • Patients who have had exfoliative dermatitis due to medication in the past should remember what medication they are allergic to and avoid using it later.


How To Treat Exfoliative Dermatitis

How is exfoliative dermatitis treated?

The most important thing is to find the primary disease or cause leading to exfoliative dermatitis and cure the primary disease or remove the cause. Skin symptoms can be relieved by topical nonirritating, protective medications such as vegetable oils, zinc oxide oil, or inefficient glucocorticoid cream.

In addition, but also to supplement nutrition, maintain the stability of water and electrolytes, pay attention to keep warm. Severe cases can be treated with glucocorticoids or gamma immunoglobulins.

Does the treatment of exfoliative dermatitis must use glucocorticoid, can you have side effect?

Generally, exfoliative dermatitis or idiopathic exfoliative dermatitis caused by drugs need to be treated with glucocorticoids. Short-term use under the guidance of a doctor without great side effects.

Can exfoliative dermatitis relapse?

  • Exfoliative dermatitis can recur, but according to the different causes, the probability of recurrence is different. For example, exfoliative dermatitis caused by drug allergy. If such drugs or drugs with similar structures are used again in the future, exfoliative dermatitis will appear again. Therefore, these drugs must be avoided.

  • And psoriasis, eczema and other skin diseases lead to exfoliative dermatitis, because the primary disease itself is not easy to cure, coupled with irregular use of drugs, it may lead to exfoliative dermatitis attack again.

  • Patients with tumors (skin T-cell lymphoma) are prone to relapses and can also lead to recurrence of exfoliative dermatitis.


What Should Exfoliative Dermatitis Patient Notice In Life

Can the patient of exfoliative dermatitis bathe?

No! Bathing does great harm to patients with exfoliative dermatitis, increasing the chance of infection and skin symptoms.

What precautions does exfoliative dermatitis patient have on food?

  • Patients with exfoliative dermatitis do not drink alcohol, do not eat spicy excitant food.

  • You can eat more high-protein foods, such as lean meat, eggs, dairy products, etc. Because it contains a large amount of protein and calcium, it can supplement the protein loss caused by desquamation, and increase the intravascular colloid osmotic pressure and reduce tissue edema.

  • Eat more fruits and vegetables, green vegetables and fruits and other rich in vitamin C, can reduce the capillary exudation, play a role in swelling and reduce skin inflammation.

  • Eat more corn, buckwheat, oats and other foods containing B vitamins and cellulose, not only can promote skin formation, but also to keep the stool unobstructed, to prevent constipation caused by long-term bed rest.

Related Articles