Opioid Overdose Poisoning (Opioid Overdose Crisis,)

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Opioid Overdose Poisoning
Body Parts: Whole Body
Medical Subjects: Digestive System Kidney
Overview

What Is Opioid Poisoning

Opioids mainly include opium, morphine, codeine, compound camphor tincture and papaverine, with morphine as the representative. The effect of morphine on the central nervous system is first excited, then inhibited, and mainly inhibited. Long-term use of opioids can cause euphoria and addiction.

Cause

What Is The Cause Of Opioid Poisoning

1. The main component of opium is morphine (about 10%). Morphine excites the central nervous system first, then inhibits it, but mainly inhibits it. The toxic dose of morphine is 0.06g, and the toxic dose of codeine is 0.2g. Long-term use of morphine can cause euphoria and addiction.

2. Excessive use of opioids.

Symptom

What Are The Symptoms Of Opioid Poisoning

1. Mild opioid poisoning is mainly manifested as headache, dizziness, nausea, vomiting, excitement or inhibition. There is a sense of illusion and loss of time and space.

2. Patients with severe poisoning may suffer from coma, respiratory depression, convulsion, clenching of teeth, and reverse extension of angle arch.

3. Chronic poisoning mainly has symptoms such as loss of appetite, constipation, emaciation, aging and sexual dysfunction.

Detect

How To Check For Opioid Poisoning

1. Urine routine.

2. Detection of stomach contents.

Opioids were detected in urine and stomach contents.

Prevention

How To Prevent Opioid Poisoning

1. Strengthen management and strictly control the use of narcotic analgesics.

2. Anti-drug, resolutely crack down on the activities of criminals who sell opioids, and carry out anti-drug on those who are poisoned.

3. After opioid poisoning is found, the poisoning route should be determined first. If the poisoning lasts for a long time, people who take it orally should wash their stomach, but apomorphine is forbidden to induce vomiting. In case of excessive morphine injected subcutaneously, use a tourniquet to tighten the injection site immediately, apply cold compress locally to delay absorption, and relax the ligation time.

4. Atropine is used to stimulate respiratory center, keep respiratory tract unobstructed and breathe oxygen when respiratory depression occurs.

5. Opioid antidote: ① Naloxone: 0.4-0.8mg intramuscular or intravenous injection. ② Nalorphine: 5-10 mg/time, intramuscular or intravenous injection, if necessary, repeated injections at intervals of 10-15 minutes.

6. Treatment of patients with chronic poisoning: gradually withdraw drugs within 2-3 weeks, and give barbiturates and other sedatives symptomatic treatment.

Treatment

How To Treat Opioid Poisoning

1. Oral poisoning should be gastric lavage or vomiting.

2. If excessive morphine is injected subcutaneously, use a tourniquet to tighten the injection site and apply cold compress locally.

3. As soon as possible with apine antidote, such as naloxone or nalorphine.

4. Symptomatic treatment: maintain respiratory function and keep respiratory tract unobstructed.

Identify

How To Identify Opioid Poisoning

Distinguish from poisoning caused by organic nitrogen pesticides, wild mushrooms, organic chlorine and poisoning. Detection of toxicants in urine or stomach contents is helpful to determine the diagnosis.

Complication

What Are The Complications Of Opioid Poisoning

He died of acute pulmonary edema, shock, dilated pupils and respiratory paralysis.

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